BioPharma - Bioprocess Development Forum

Articles BioPharma

January 26, 2023

Reducing the Risk of RNAse Contamination in mRNA Production

As drug and vaccine manufacturers work to optimize mRNA production processes, one hurdle to overcome...

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Articles BioPharma Downstream Upstream

January 13, 2022

Enhancing Resins Addresses Purification Concerns

There is ongoing enhancement of downstream chromatography resins as biomanufacturers...

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Articles BioPharma Downstream Upstream

November 4, 2021

Large-Scale Single-Use Bioreactors Prove Mettle Amid Growing Demand

The 2000-L-scale SUB has been the mainstay of large-scale SUBs since its introduction. Yasser...

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Articles BioPharma Downstream Regulatory Upstream

August 30, 2021

Cell-free Expression Systems Pose Cell Culture Alternative

Among the challenges in upstream bioprocessing is the cellular waste generated as a by-product...

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Articles BioPharma Downstream Upstream

August 30, 2021

Single-Use Technologies Prove Effective for Viral Vector Process Development

Upstream viral-vector processes can have significant impacts on downstream purification requirements. The presence...

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Articles BioPharma Downstream Regulatory Upstream

June 17, 2021

Innovative Chromatography Resins Can Improve Purity and Quality

With ongoing efforts to increase monoclonal antibody (mAb) productivity in large-scale biomanufacturing...

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Articles BioPharma Downstream Regulatory Upstream

February 25, 2021

Remote Monitoring and Big Data Advance Upstream Automation

As upstream processing drives toward higher efficiencies in meeting demand, it requires optimizing...

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Articles BioPharma Downstream Regulatory Upstream

January 14, 2021

Updating Viral Clearance for New Biologic Modalities

Viral clearance processes and guidance must evolve along with newer biotherapeutic modalities.

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Articles BioPharma Downstream Regulatory

December 17, 2020

Virus-like Particles as Therapeutic Moieties of the Future

Virus-like particles (VLPs) are viral capsid shells assembled without encapsulated nucleic acid.

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Articles BioPharma Downstream Regulatory

July 30, 2020

Improving mAb Manufacturing Productivity by Optimizing Buffer and Media Prep Process Flow

It is common for biologics manufacturing processes to require hundreds of raw materials...

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