BioPharma - Bioprocess Development Forum

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February 28, 2019

Bispecific Antibody Purification: Insights and Case Studies

New modalities, like bispecific antibodies, present unique challenges compared to mAb production.

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February 14, 2019

Supply Chain Challenges for Single-Use Systems

The implementation of single-use systems (SUS) for biopharmaceutical manufacturing as an alternative...

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Articles BioPharma Downstream Upstream

January 31, 2019

Modeling the Degradation of mAb Therapeutics

Ensuring the stability of biotherapeutic products, which has an impact on their safety and...

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Articles BioPharma Downstream

January 17, 2019

A Look at the Affinity Chromatography Landscape

Affinity chromatography offers the high selectivity required for biopharmaceutical manufacturing and analysis. Specific binding...

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Articles BioPharma Downstream Regulatory

December 20, 2018

Achieving Process Balance with Perfusion Bioreactors

Perfusion cell-culture processes have been used for more than two decades for the production of...

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Articles BioPharma Downstream Regulatory

September 27, 2018

Ensuring Viral Safety of Viral Vaccines and Vectors

Vaccines, including viral vaccines, are a crucial invention in human history and continue to...

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Articles BioPharma Downstream Upstream

July 2, 2018

Challenges in Cell Harvesting Prompt Enhancements

Cell harvesting is a crucial step that can have significant impact on product quality and…

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Articles BioPharma Downstream Regulatory

June 7, 2018

Putting Viral Clearance Capabilities to the Test

Drug products based on live cells have an inherent risk for viral contamination that could…

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Articles BioPharma Regulatory

April 12, 2018

Understanding Validation and Technical Transfer, Part I

Many new biological entities use unique processing flows and steps that can require non-traditional...

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Articles BioPharma Regulatory

March 1, 2018

Efficient Cleaning-In-Place Methods for Protein-Based Antibody Affinity Chromatography Resins

This whitepaper discusses cleaning of affinity resins for purifying monoclonal antibodies and Fab fragments…

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