Downstream - Bioprocess Development Forum

Articles BioPharma Downstream Regulatory Upstream

May 21, 2020

Gene Therapies Push Viral Vector Production

Several virus types have been studied for use as viral vectors in gene therapy, including…

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Articles Downstream Upstream

March 12, 2020

Improving Upstream Predictability

In the earliest days of biotech, developers often struggled to sustain conditions that would...

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Articles Downstream Upstream

March 12, 2020

Flexible Facilities for Viral Vector Manufacturing

Industry experts have noted that there are limitations in the number of scalable...

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Articles BioPharma Downstream Upstream

February 27, 2020

Maximizing the Effectiveness of Upstream Bioprocessing Through the Combination of Lab Informatics and Instrumentation

The biopharmaceutical market continues to expand at a rapid pace and the demand for upstream...

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Articles Downstream

February 13, 2020

Purification of Plasmid DNA

Plasmid DNA is the building block of advanced therapies. As these therapies take off, so…

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Articles Downstream Upstream

January 30, 2020

Mapping a Route for Cell and Gene Therapy Process Development

The regenerative medicine field is still quite young, and companies developing commercial processes...

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Articles Downstream Upstream

December 5, 2019

New Therapies Present Scaling Challenges

Manufacturing differences between traditional mAb therapies and newer biotherapeutics dictate whether...

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Articles Downstream Upstream

October 24, 2019

Next Generation Bioprocesses: Mapping Roads to the Future

Increased productivity demand and a diversifying clinical drug pipeline have pushed the industry...

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Articles Downstream Regulatory

October 24, 2019

Best Practices for Selecting a Top-Quality Cell Line

Leveraging automation and a step-by-step approach are keys to success. Cell lines determine the...

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Articles Downstream Upstream

August 15, 2019

Monitoring and Control of Inline Dilution Processes

Buffer management has received less attention in process intensification despite the high costs and...

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