Downstream - Bioprocess Development Forum

Articles BioPharma Downstream Upstream

August 11, 2017

Process Chromatography: Continuous Optimization

Cell-culture and fermentation are high-yielding processes that effectively produce...

admin-element

Articles Downstream Regulatory Upstream

June 14, 2017

Managing Residual Impurities During Downstream Processing

Increased understanding of potential impurities has spurred efforts to standardize monitoring procedures.

admin-element

Articles BioPharma Downstream Regulatory

May 4, 2017

Being Thorough When Transferring Technology

Tech transfer and scale up of biologics can be as complicated as biologic therapies themselves.

admin-element

Articles Downstream

April 19, 2017

Mechanistic Modeling of Preparative Ion-Exchange Chromatography

Among the various downstream processing unit operations that are used for purification of biotech...

admin-element

Articles Downstream Regulatory Upstream

April 19, 2017

Downstream Processing for Cell-Based Therapies

With increasing numbers of advanced therapies—including cell and gene therapies—entering early- and...

admin-element

Articles BioPharma Downstream Regulatory Upstream

April 5, 2017

Single-use Bioreactors Have Reached the Big Time

Single-use bioreactors available from various vendors today are robust and provide the high-performance...

admin-element

Articles Downstream Regulatory Upstream

November 10, 2016

Improving Process-Scale Chromatography

Chromatography is a crucial step in the purification of biopharmaceuticals and accounts for a...

admin-element

Articles Downstream Upstream

September 14, 2016

Process Chromatography Selection for Downstream Processing Applications

Industry experts discuss best practices for selecting a separation technology. Process chromatography...

admin-element

Articles Downstream Regulatory Upstream

May 25, 2016

An Integrated Approach to Ensure the Viral Safety of Biotherapeutics

Use of continuous cell lines in the manufacture of biological therapeutic products, such as...

admin-element

Articles Downstream Regulatory Upstream

April 14, 2016

Continuous Processing for the Production of Biopharmaceuticals

The biosimilars landscape is growing as market factors, such as pricing pressure, advanced...

admin-element