Downstream - Bioprocess Development Forum

Articles BioPharma Downstream Regulatory Upstream

September 21, 2017

Bioburden Control in the Biopharmaceutical Industry

The biopharmaceutical industry has witnessed tremendous breakthroughs during the past few years. However, this advancement...

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Articles BioPharma Downstream

September 21, 2017

Impact of Media Components on CQAs of Monoclonal Antibodies

Recombinant protein products have made a revolutionary impact on human healthcare by enabling mass...

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Articles BioPharma Downstream Regulatory Upstream

September 7, 2017

The Role of Quality Standards for Biomanufacturing Raw Materials

Successful pharmaceutical manufacturing strategies depend on raw materials that are of good quality.

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Articles BioPharma Downstream Upstream

August 11, 2017

Process Chromatography: Continuous Optimization

Cell-culture and fermentation are high-yielding processes that effectively produce...

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Articles Downstream Regulatory Upstream

June 14, 2017

Managing Residual Impurities During Downstream Processing

Increased understanding of potential impurities has spurred efforts to standardize monitoring procedures.

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Articles BioPharma Downstream Regulatory

May 4, 2017

Being Thorough When Transferring Technology

Tech transfer and scale up of biologics can be as complicated as biologic therapies themselves.

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Articles Downstream

April 19, 2017

Mechanistic Modeling of Preparative Ion-Exchange Chromatography

Among the various downstream processing unit operations that are used for purification of biotech...

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Articles Downstream Regulatory Upstream

April 19, 2017

Downstream Processing for Cell-Based Therapies

With increasing numbers of advanced therapies—including cell and gene therapies—entering early- and...

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Articles BioPharma Downstream Regulatory Upstream

April 5, 2017

Single-use Bioreactors Have Reached the Big Time

Single-use bioreactors available from various vendors today are robust and provide the high-performance...

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Articles Downstream Regulatory Upstream

November 10, 2016

Improving Process-Scale Chromatography

Chromatography is a crucial step in the purification of biopharmaceuticals and accounts for a...

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