ArticlesDownstream April 8, 2015 Re-use of Protein A Resin: Fouling and Economics In the past two decades, Protein A affinity chromatography has remained the de facto capture… admin-element
ArticlesBioPharmaDownstreamRegulatoryUpstream April 8, 2015 Continuous Manufacturing: A Changing Processing Paradigm Although continuous manufacturing is well established for bulk chemicals, complex automation and... admin-element
ArticlesBioPharmaDownstreamRegulatoryUpstream April 6, 2015 Use of Multivariate Data Analysis in Bioprocessing The ever increasing demand of biotherapeutics, together with the pressure to contain healthcare... admin-element
ArticlesDownstreamRegulatoryUpstream November 1, 2014 Viral Clearance Challenges in Bioprocessing Removal and inactivation of adventitious and endogenous viruses have traditionally been achieved... admin-element
ArticlesBioPharmaDownstreamRegulatoryUpstream October 29, 2014 Application of Quality by Design to Viral Safety The biotech industry has begun to implement a quality-by-design (QbD) approach to ensure the... admin-element
ArticlesBioPharmaDownstreamUpstream September 1, 2014 Challenges of Protein Aggregation During Purification Removal of protein aggregates from biologic APIs is crucial due to their potential to increase... admin-element
ArticlesDownstream July 17, 2014 Analyzing Proteins Using SEC, MALS, and UHPLC Light scattering analysis combined with more rapid size exclusion chromatography improves protein... admin-element
ArticlesDownstream January 27, 2014 Determining Criticality, Part Two: DoE and Data-Driven Criticality A practical roadmap in three parts that applies scientific knowledge, risk analysis, experimental... admin-element
ArticlesDownstreamRegulatoryUpstream January 13, 2014 PDA’s Technical Report for Biotech Cleaning Validation Cleaning validation plays an important role in reducing the possibility of product contamination... admin-element
ArticlesDownstream November 22, 2013 Evolution of the Monoclonal Antibody Purification Platform BioPharm InternationalBy: Anurag S. Rathore, Ranga Godavarti, Vijesh Kumar, Nihal Tugcu for BioPharm International The… Derek Author Smith