Downstream - Bioprocess Development Forum

Articles Downstream

March 9, 2023

Modern plasmid purification process

AcuraBio selects Cytiva's latest two-step purification protocol to offer a productive plasmid DNA...

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Articles Downstream

February 23, 2023

Protein L affinity resin is ready to move to manufacturing

Although protein L affinity resins have been available for more than a decade, insufficient binding...

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Articles Downstream

February 9, 2023

Download your Mechanistic Modeling eBook

Mechanistic models use computer simulations to decrease the number of experiments needed during...

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Articles Downstream

February 9, 2023

Choose your Optimal Wavelength for Chromatography

ÄKTA™ chromatography systems and resins offer a wide range of solutions for isolating and purifying...

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Articles BioPharma Downstream Upstream

January 13, 2022

Enhancing Resins Addresses Purification Concerns

There is ongoing enhancement of downstream chromatography resins as biomanufacturers...

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Articles BioPharma Downstream Upstream

November 4, 2021

Large-Scale Single-Use Bioreactors Prove Mettle Amid Growing Demand

The 2000-L-scale SUB has been the mainstay of large-scale SUBs since its introduction. Yasser...

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Articles Downstream Upstream

September 9, 2021

Antibody Production Workflow

Antibody-based therapies have evolved beyond monoclonal antibodies (mAbs) to include bispecific...

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Articles BioPharma Downstream Regulatory Upstream

August 30, 2021

Cell-free Expression Systems Pose Cell Culture Alternative

Among the challenges in upstream bioprocessing is the cellular waste generated as a by-product...

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Articles BioPharma Downstream Upstream

August 30, 2021

Single-Use Technologies Prove Effective for Viral Vector Process Development

Upstream viral-vector processes can have significant impacts on downstream purification requirements. The presence...

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Articles Downstream

August 30, 2021

How to Optimize and Scale Up AAV Production

In this article from a roundtable discussion, four experts from academia and industry met to discuss...

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