Downstream - Bioprocess Development Forum

Articles Downstream Regulatory Upstream

July 15, 2021

Assessing Manufacturing Process Robustness

The pharmaceutical regulatory landscape and pharmaceutical development have been reshaped by...

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Articles BioPharma Downstream Regulatory Upstream

June 17, 2021

Innovative Chromatography Resins Can Improve Purity and Quality

With ongoing efforts to increase monoclonal antibody (mAb) productivity in large-scale biomanufacturing...

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Articles Downstream Regulatory

April 22, 2021

Guide to Polishing Chromatography in Process Development

This article shares the factors you should consider when developing your polishing steps...

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Articles Downstream Regulatory Upstream

March 25, 2021

Basics in Process Development for Biotherapeutics

Definitions, activities, and things to consider when developing an upstream or downstream bioprocess.

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Articles BioPharma Downstream Regulatory Upstream

February 25, 2021

Remote Monitoring and Big Data Advance Upstream Automation

As upstream processing drives toward higher efficiencies in meeting demand, it requires optimizing...

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Articles BioPharma Downstream Regulatory Upstream

January 14, 2021

Updating Viral Clearance for New Biologic Modalities

Viral clearance processes and guidance must evolve along with newer biotherapeutic modalities.

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Articles BioPharma Downstream Regulatory

December 17, 2020

Virus-like Particles as Therapeutic Moieties of the Future

Virus-like particles (VLPs) are viral capsid shells assembled without encapsulated nucleic acid.

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Articles Downstream

November 19, 2020

Developing a Continuous Large-Scale Perfusion Cell Culture Process

Perfusion processes enable continuous operation over extended periods of time by constantly providing...

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Articles Downstream Regulatory Upstream

November 5, 2020

Reimagining Affordable Biosimilars

Drug development is undergoing a transformation from multi-billion-dollar blockbusters to personalized...

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Articles Downstream Upstream

July 30, 2020

Lentiviral Vector Upstream Process in Single-use Bioreactors

Lentiviruses exhibit many desirable properties as gene transfer vehicles, such as high transduction...

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