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January 12, 2023
rAAV Production Using HEK293 Cell Line and Transfection Medium
Improving the performance of a scalable AAV process in Xcellerex™ XDR-10 and XDR-200 bioreactor...
January 13, 2022
Enhancing Resins Addresses Purification Concerns
There is ongoing enhancement of downstream chromatography resins as biomanufacturers...
November 18, 2021
Scaling Up an E. coli Upstream Process for Plasmid DNA Production — from 2.5 to 160 L scale Fermenters
This article summarizes the results of Escherichia coli growth performance for plasmid...
November 18, 2021
Maximum Output Starts with Optimized Upstream Processing
Significant growth in the development and manufacturing of biologics—from traditional recombinant...
November 4, 2021
Large-Scale Single-Use Bioreactors Prove Mettle Amid Growing Demand
The 2000-L-scale SUB has been the mainstay of large-scale SUBs since its introduction. Yasser...
October 21, 2021
Cell Culture Media Selection Guide for Your Lab Wall
Doing cell culture and upstream process development on antibodies, vaccines, or viruses?
September 9, 2021
Antibody Production Workflow
Antibody-based therapies have evolved beyond monoclonal antibodies (mAbs) to include bispecific...
August 30, 2021
Cell-free Expression Systems Pose Cell Culture Alternative
Among the challenges in upstream bioprocessing is the cellular waste generated as a by-product...