Upstream - Bioprocess Development Forum

Articles BioPharma Upstream

February 18, 2016

Antibody Production in Microbial Hosts

The biopharmaceutical industry is growing exponentially, driven by an ever-increasing demand for monoclonal antibodies (mAbs)…

admin-element

Articles BioPharma Downstream Upstream

January 21, 2016

Going Small to Achieve Success on the Commercial Scale

Biopharmaceutical manufacturing involves a series of complex unit operations linked together to...

admin-element

Articles BioPharma Downstream Regulatory Upstream

November 19, 2015

Selecting the Right Viral Clearance Technology

The introduction of adventitious viral agents is a recognized, inherent risk of biologic drug...

admin-element

Articles BioPharma Downstream Regulatory Upstream

September 10, 2015

Best Practices in Qualification of Single-Use Systems

Single-use technology has been around for approximately two decades if disposable capsule filters...

admin-element

Articles Downstream Regulatory Upstream

June 4, 2015

Host-Cell Protein Measurement and Control

Host-cell proteins (HCPs) constitute a major part of process-related impurities during biologics...

admin-element

Articles BioPharma Downstream Regulatory Upstream

April 8, 2015

Continuous Manufacturing: A Changing Processing Paradigm

Although continuous manufacturing is well established for bulk chemicals, complex automation and...

admin-element

Articles BioPharma Downstream Regulatory Upstream

April 6, 2015

Use of Multivariate Data Analysis in Bioprocessing

The ever increasing demand of biotherapeutics, together with the pressure to contain healthcare...

admin-element

Articles BioPharma Upstream

February 26, 2015

Quality by Design and Extractable and Leachable Testing

Biopharmaceutical packaging performs several vital functions in assuring the drug product safety.

admin-element

Articles Upstream

December 3, 2014

Trends in Single-use Bioreactors

While the overall trend toward single-use bioreactors is generally positive, users continue to have...

admin-element

Articles Downstream Regulatory Upstream

November 1, 2014

Viral Clearance Challenges in Bioprocessing

Removal and inactivation of adventitious and endogenous viruses have traditionally been achieved...

admin-element