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June 2, 2022
e-Learning: what is quality by design (QbD)?
This free interactive course shares what quality by design (QbD) is all about. The focus…
April 7, 2022
Next-generation protein L chromatography
Use protein L affinity chromatography to capture bispecific antibodies and antibody fragments...
February 24, 2022
Mechanistic vs Statistical Models
Mathematical models are recommended by the ICH Q8 guidelines on pharmaceutical development to...
January 13, 2022
Enhancing Resins Addresses Purification Concerns
There is ongoing enhancement of downstream chromatography resins as biomanufacturers...
November 18, 2021
Scaling Up an E. coli Upstream Process for Plasmid DNA Production — from 2.5 to 160 L scale Fermenters
This article summarizes the results of Escherichia coli growth performance for plasmid...
November 18, 2021
Maximum Output Starts with Optimized Upstream Processing
Significant growth in the development and manufacturing of biologics—from traditional recombinant...
November 4, 2021
Large-Scale Single-Use Bioreactors Prove Mettle Amid Growing Demand
The 2000-L-scale SUB has been the mainstay of large-scale SUBs since its introduction. Yasser...
October 21, 2021
Cell Culture Media Selection Guide for Your Lab Wall
Doing cell culture and upstream process development on antibodies, vaccines, or viruses?
October 21, 2021
Scalable AAV Production Process for Gene Therapy
Viral vectors are often used for gene transfer of specific tissue- or cell-type modifications.