Articles - Bioprocess Development Forum

Articles Upstream

January 17, 2019

Perfusion Culture Using TFF or ATF as Cell Retention Method

Perfusion processes have many advantages such as being favorable for product quality and...

admin-element

Articles BioPharma Downstream Regulatory

December 20, 2018

Achieving Process Balance with Perfusion Bioreactors

Perfusion cell-culture processes have been used for more than two decades for the production of...

admin-element

Articles BioPharma Downstream Regulatory

September 27, 2018

Ensuring Viral Safety of Viral Vaccines and Vectors

Vaccines, including viral vaccines, are a crucial invention in human history and continue to...

admin-element

Articles

September 27, 2018

How to Determine Dynamic Binding Capacity (DBC) of Chromatography Resins

In protein purification, dynamic binding capacity (DBC) of a chromatography column describes the...

admin-element

Articles Downstream

July 2, 2018

Developing an Efficient Adenovirus Downstream Purification Process

Adenovirus is one of the most frequently used viral vectors in the development of therapeutic...

admin-element

Articles BioPharma Downstream Upstream

July 2, 2018

Challenges in Cell Harvesting Prompt Enhancements

Cell harvesting is a crucial step that can have significant impact on product quality and…

admin-element

Articles BioPharma Downstream Regulatory

June 7, 2018

Putting Viral Clearance Capabilities to the Test

Drug products based on live cells have an inherent risk for viral contamination that could…

admin-element

Articles

May 24, 2018

Chromatography Scale-Up: Don’t Get Tied Down by Bed Height

When scaling, you can make better use of existing chromatography columns while avoiding overcapacity.

admin-element

Articles Multimedia

May 24, 2018

Cleaning Protein A Resins with 1 M NaOH

With increasing mAb titers, the impurity level of the cell culture feed increases. If not…

admin-element

Articles

May 9, 2018

Capacity and Performance of a Next Generation Protein A Chromatography Resin

MabSelect™ PrismA is a protein A resin of which both the ligand and the base…

admin-element