Articles - Bioprocess Development Forum

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August 13, 2015

Optimizing Cation-Exchange Chromatography with High-Throughput Process Development for mAb Purification

An important area of focus for the biopharma industry is the elucidation and development of...

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July 15, 2015

Risk Assessment and Mitigation in Biopharmaceutical Manufacturing

BioPharm International spoke with Stephan Krause, director of quality assurance, Laura Jeannel...

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July 15, 2015

Robust Optimization, Simulation, and Effective Design Space

Developing product knowledge and process understanding is at the heart of modern drug...

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June 4, 2015

Host-Cell Protein Measurement and Control

Host-cell proteins (HCPs) constitute a major part of process-related impurities during biologics...

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May 7, 2015

Optimization of Protein Expression in Escherichia Coli

Production of proteins for manufacturing therapeutics and pharmaceuticals is a complicated process...

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May 1, 2015

Modular Manufacturing Platforms for Biologics

It should come as no surprise that the good design principles governing pharmaceutical manufacturing…

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April 23, 2015

Continuous Chromatography: Trends, Definitions and Approaches

There is a lot of attention being paid to continuous chromatography, and several different terms...

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Articles Regulatory

April 8, 2015

USP Publishes Monoclonal Antibody Guidelines

As FDA gears up towards approving biosimilar drugs in the United States, it is unquestionable...

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April 8, 2015

Re-use of Protein A Resin: Fouling and Economics

In the past two decades, Protein A affinity chromatography has remained the de facto capture…

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April 8, 2015

Continuous Manufacturing: A Changing Processing Paradigm

Although continuous manufacturing is well established for bulk chemicals, complex automation and...

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