Articles - Bioprocess Development Forum

Articles Downstream

July 11, 2024

Buffer optimization for separation of bsAb in a capture step using MabSelect™ VL resin

Protein L resins bind to kappa light chain and are often used to purify antibody…

Ross Burns

Articles Upstream

June 27, 2024

Innovations in perfusion bioprocessing

In this study, we present a method for deriving perfusion culture media by leveraging existing…

Ross Burns

Articles Downstream Upstream

June 27, 2024

From bottlenecks to breakthroughs: Mastering buffer management

Unlock innovation in manufacturing by optimizing your buffer production. Traditional process liquid and buffer

Ross Burns

Articles Multimedia Regulatory Regulatory

June 13, 2024

Extractables in single-use systems used in ADC manufacturing, Part 2.

We performed extractables studies on single-use chromatography and tangential flow filtration systems using common solvents…

Ross Burns

Articles Downstream

June 13, 2024

In silico optimization of AAV full/empty particle separation with AIEX

The separation of adeno-associated virus (AAV) with high yield and purity is an increasingly important…

Ross Burns

Articles Downstream

June 13, 2024

Process development using a nonaffinity method vs Cytiva™ Protein Select™ resin

In this study, we compared two approaches for purifying a recombinant protein that does not…

Ross Burns

Articles Downstream

May 30, 2024

Webinar: Intensifying downstream bioprocessing with continuous technologies.

Significant operational improvements can be achieved by intensified continuous processes compared to standard batch processes.

Ross Burns

Articles Upstream

April 18, 2024

Unraveling the secrets of poloxamer 188 – A webinar mystery

When an inexplicable drop in cell culture performance is linked to a batch of media,…

Ross Burns

Articles BioPharma Regulatory

April 5, 2024

Filtration methods to overcome new challenges in viral safety

Read our article which summarizes the recent virus filtration regulatory changes in PDA Technical...

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Articles BioPharma

April 5, 2024

A Closer Look at Affinity Ligands

Affinity ligands play an exciting role in the ever-growing sphere of downstream processing.

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