There’s no ‘one size fits all’ solution for optimizing mAb capture
What determines the optimal protein A capture resin for a given mAb process? The scale, mode of operation, and batch frequency, among other factors.
During clinical operation, resins made for large-scale manufacturing are rarely used to their full lifetime. On the other hand, in the latter scenario a productive protein A step needs to run at high flow rates, using a high – capacity, high – durability resin to allow for a long lifetime and cost-efficiency.
What should you consider to develop a cost-efficient protein A step for your reality?
