ArticlesDownstream April 19, 2017 Mechanistic Modeling of Preparative Ion-Exchange Chromatography Among the various downstream processing unit operations that are used for purification of biotech... admin-element
ArticlesDownstreamRegulatoryUpstream April 19, 2017 Downstream Processing for Cell-Based Therapies With increasing numbers of advanced therapies—including cell and gene therapies—entering early- and... admin-element
ArticlesBioPharmaDownstreamRegulatoryUpstream April 5, 2017 Single-use Bioreactors Have Reached the Big Time Single-use bioreactors available from various vendors today are robust and provide the high-performance... admin-element
ArticlesBioPharma February 23, 2017 Impact of Manufacturing-Scale Freeze-Thaw Conditions on a mAb Solution The objective of this study was to assess the impact of manufacturing-scale, freeze-thaw conditions... admin-element
ArticlesBioPharma February 23, 2017 Ensuring the Biological Integrity of Raw Materials Contamination with microbes, mycoplasma, viruses, and other adventitious agents can be a significant... admin-element
Articles February 9, 2017 Protein Purification Troubleshooting Guide Practical advice to significantly impact your chromatography workflow. Put this poster on your... admin-element
Articles November 10, 2016 Development of column packing methods based on pressure flow measurements Scale-up of a chromatography process might appear as simply increasing the column diameter to accommodate… admin-element
ArticlesDownstreamRegulatoryUpstream November 10, 2016 Improving Process-Scale Chromatography Chromatography is a crucial step in the purification of biopharmaceuticals and accounts for a... admin-element
ArticlesRegulatory October 10, 2016 Establishing Acceptance Criteria for Analytical Methods To control the consistency and quality of pharmaceutical products, analytical methods must be... admin-element
Articles September 29, 2016 Modeling Bioreactor Performance Bioreactor design, including the geometry of the tank and impeller and the locations of inlets... admin-element