chromatography - Bioprocess Development Forum

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May 24, 2018

Cleaning Protein A Resins with 1 M NaOH

With increasing mAb titers, the impurity level of the cell culture feed increases. If not…

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Articles

May 9, 2018

Capacity and Performance of a Next Generation Protein A Chromatography Resin

MabSelect™ PrismA is a protein A resin of which both the ligand and the base…

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Multimedia

November 17, 2017

Handbook: Design of Experiments in Protein Production and Purification

Design of experiments (DoE) is a technique for planning experiments and analyzing the information...

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Articles BioPharma Downstream Upstream

August 11, 2017

Process Chromatography: Continuous Optimization

Cell-culture and fermentation are high-yielding processes that effectively produce...

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Articles

February 9, 2017

Protein Purification Troubleshooting Guide

Practical advice to significantly impact your chromatography workflow. Put this poster on your...

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Articles

November 10, 2016

Development of column packing methods based on pressure flow measurements

Scale-up of a chromatography process might appear as simply increasing the column diameter to accommodate…

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November 10, 2016

Improving Process-Scale Chromatography

Chromatography is a crucial step in the purification of biopharmaceuticals and accounts for a...

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Multimedia

June 9, 2016

Selection Guide Size Exclusion Chromatography Columns and Media

Size exclusion chromatography (SEC), also called Gel filtration (GF), separates molecules on the...

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November 19, 2015

Selecting the Right Viral Clearance Technology

The introduction of adventitious viral agents is a recognized, inherent risk of biologic drug...

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August 13, 2015

Optimizing Cation-Exchange Chromatography with High-Throughput Process Development for mAb Purification

An important area of focus for the biopharma industry is the elucidation and development of...

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