chromatography - Bioprocess Development Forum

Articles BioPharma Downstream Upstream

August 11, 2017

Process Chromatography: Continuous Optimization

Cell-culture and fermentation are high-yielding processes that effectively produce...

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Articles

February 9, 2017

Protein Purification Troubleshooting Guide

Practical advice to significantly impact your chromatography workflow. Put this poster on your...

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Articles

November 10, 2016

Development of column packing methods based on pressure flow measurements

Scale-up of a chromatography process might appear as simply increasing the column diameter to accommodate…

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Articles Downstream Regulatory Upstream

November 10, 2016

Improving Process-Scale Chromatography

Chromatography is a crucial step in the purification of biopharmaceuticals and accounts for a...

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Multimedia

June 9, 2016

Selection Guide Size Exclusion Chromatography Columns and Media

Size exclusion chromatography (SEC), also called Gel filtration (GF), separates molecules on the...

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Articles BioPharma Downstream Regulatory Upstream

November 19, 2015

Selecting the Right Viral Clearance Technology

The introduction of adventitious viral agents is a recognized, inherent risk of biologic drug...

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Articles Downstream

August 13, 2015

Optimizing Cation-Exchange Chromatography with High-Throughput Process Development for mAb Purification

An important area of focus for the biopharma industry is the elucidation and development of...

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Articles Downstream

April 8, 2015

Re-use of Protein A Resin: Fouling and Economics

In the past two decades, Protein A affinity chromatography has remained the de facto capture…

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Articles

March 26, 2015

Handbook: Size Exclusion Chromatography Principles and Methods

This handbook describes the use of SEC for the purification and separation of biomolecules, with…

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Articles Regulatory

October 17, 2014

Using Quality by Design to Develop Robust Chromatographic Methods

The quality-by-design principles that enable a manufacturer to limit and control the sources of process…

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