ArticlesDownstreamDownstreamEvents November 1, 2024 On-demand webinar: In silico process development for AAVs – Learn from MeiraGTx CytivaThe biotherapeutics pipeline is evolving and so are the tools to purify and manufacture therapeutic… Jeanne Linke
ArticlesDownstreamDownstreamMultimedia August 22, 2024 Download the infographic about viral vector manufacturing Crafting a downstream viral vector process that's budget-friendly and GMP-ready is no small feat. But… Ross Burns
ArticlesDownstream April 5, 2024 Exosome isolation by tangential flow filtration and size exclusion chromatography We demonstrate a scalable workflow for the isolation of exosomes—a type of extracellular vesicle... admin-element
Articles January 26, 2024 A scalable single-use two-step plasmid purification process The current global demand for biopharmaceuticals is over USD 300 billion, with an estimated growth... admin-element
ArticlesRegulatory January 12, 2024 Dear lentivirus: We have not forgotten about you and how to improve your polishing recovery Lentiviruses are commonly used for both chimeric antigen receptor (CAR) T cell therapy and ex... admin-element
ArticlesDownstream December 15, 2023 A deep dive into optimizing AAV capture and polishing to maximize both yield and purity As demand for AAV vectors grows, so does the need for scalable and cost-efficient purification... admin-element
ArticlesBioPharma August 25, 2023 Balancing AAVs Versus LLVs Knowledge of adeno-associated variant's infection pathway is based on only a few serotypes. admin-element
ArticlesDownstream March 9, 2023 Modern plasmid purification process AcuraBio selects Cytiva's latest two-step purification protocol to offer a productive plasmid DNA... admin-element
ArticlesUpstream January 12, 2023 rAAV Production Using HEK293 Cell Line and Transfection Medium Improving the performance of a scalable AAV process in Xcellerex™ XDR-10 and XDR-200 bioreactor... admin-element
ArticlesUpstream November 18, 2021 Scaling Up an E. coli Upstream Process for Plasmid DNA Production — from 2.5 to 160 L scale Fermenters This article summarizes the results of Escherichia coli growth performance for plasmid... admin-element