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January 17, 2019
A Look at the Affinity Chromatography Landscape
Affinity chromatography offers the high selectivity required for biopharmaceutical manufacturing and analysis. Specific binding...
May 24, 2018
Cleaning Protein A Resins with 1 M NaOH
With increasing mAb titers, the impurity level of the cell culture feed increases. If not…
March 1, 2018
Efficient Cleaning-In-Place Methods for Protein-Based Antibody Affinity Chromatography Resins
This whitepaper discusses cleaning of affinity resins for purifying monoclonal antibodies and Fab fragments…
February 23, 2017
Impact of Manufacturing-Scale Freeze-Thaw Conditions on a mAb Solution
The objective of this study was to assess the impact of manufacturing-scale, freeze-thaw conditions...
August 13, 2015
Optimizing Cation-Exchange Chromatography with High-Throughput Process Development for mAb Purification
An important area of focus for the biopharma industry is the elucidation and development of...
April 8, 2015
USP Publishes Monoclonal Antibody Guidelines
As FDA gears up towards approving biosimilar drugs in the United States, it is unquestionable...
April 8, 2015
Re-use of Protein A Resin: Fouling and Economics
In the past two decades, Protein A affinity chromatography has remained the de facto capture…