resin - Bioprocess Development Forum

Articles Downstream

August 22, 2024

Buffer optimization for bsAb separation in a capture step using MabSelect™ VL protein L resin

Protein L resins bind to the antibody kappa light chain and can be used for…

Ross Burns

Articles Downstream

August 13, 2024

A high-throughput study of sodium hydroxide cleaning efficiency for protein A resin

Cleaning-in-place (CIP) of chromatography resins is important for the integrity and safety of the final…

Ross Burns

Articles Downstream

February 9, 2024

Selecting Chromatography Resins for Bispecific Antibody Purification

Targeting enhancement with two active antibody arms makes bispecific antibodies (bsAbs) highly at...

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Articles Downstream

February 9, 2024

Get Started: Purification of mAb Variants – eLearning

The success of monoclonal antibodies (mAbs) as therapeutics and the multi-domain structure of...

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Articles

January 26, 2024

Chromatography innovations for the diversified antibody pipeline

Introducing MabSelect™ VH3 affinity resin for antibody variants. At Cytiva, we connect with...

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Articles Downstream

February 23, 2023

Protein L affinity resin is ready to move to manufacturing

Although protein L affinity resins have been available for more than a decade, insufficient binding...

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Articles Regulatory

May 20, 2021

Evaluation of Fibro PrismA for Scalable Single-Use mAb Purification

In clinical monoclonal antibody (mAb) manufacturing, capture on protein A chromatography resin gives...

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Articles BioPharma Downstream Regulatory Upstream

July 2, 2019

Addressing the Complex Nature of Downstream Processing with QbD

Regulators have been encouraging bio/pharmaceutical companies to incorporate the concept of...

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Articles

April 25, 2019

How To Interpret Protein Binding Capacity: Chromatography Resins

The comparison between protein binding capacities of resin from different suppliers is not...

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Articles

September 27, 2018

How to Determine Dynamic Binding Capacity (DBC) of Chromatography Resins

In protein purification, dynamic binding capacity (DBC) of a chromatography column describes the...

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