Search results for " simulation"
Article
Developing a HIC polishing step for removal of mAb aggregates
It includes:
- The use of HTPD plates to select the optimal resin as well as running conditions
- The use of a design of experiments (DoE) to optimize the running conditions
- A Monte Carlo simul…
Article
Current Techniques and Challenges Presented in Scaling Between Bioreactors
cell culture
In this video, Andreas Castan, Strategic Technology Partnerships Leader at Cytiva, discusses the current techniques and challenges in scaling between bioreactors.
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Article
Mechanistic chromatography models in a nutshell
Find out how mechanistic modeling simulates what happens in your chromatography columns.
Watch the animation >>
Article
Cytiva Acquires GoSilico and Strengthens Digital Capabilities in Bioprocessing
The scientific software maker GoSilico creates “digital twins” of downstream processes, a method that is increasingly used to enhance process development by simulation. Mechanistic modelling saves tim…
Article
Increase Efficiency in Your Manufacturing with the Right Buffer Management Strategy
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Date: Wednesday, January 27, 2021
Time: 10:00 AM Eastern Standard Time
Register for our free webinar, where we compare traditional buffer preparation with outsou…
Article
Technology Innovations Improve Process Chromatography Performance
As technology matures, inefficiencies and process limitations in downstream process chromatography are improved.
By Feliza Mirasol
Selecting an appropriate separation technology fo…
Article
Biomanufacturing: Demand for Continuous Bioprocessing Increasing
Biomanufacturing: Demand for Continuous Bioprocessing Increasing
But are innovations sufficient to increase adoption? CMOs are demanding better continuous bioprocessing options. …
Article
Can Vaccine Development Be Safely Accelerated?
To develop a new vaccine, Inovio first converts the virus’ RNA into DNA and identifies short sections that will, according to computer simulations, generate the greatest immune response. The plasmids …
Article
Moving PAT from Concept to Reality
Furthermore, through real-time univariate and multivariate process monitoring, data can be used for simulation and modeling of process design and control and ultimately lead to prescriptive analytics …
Article
Leveraging Computational Models of Glycosylation for Biopharma QA
…nstraint-based linear programming (29,30) or probabilistic methods, such as Markov chain Monte Carlo simulations (31,32). A key advantage of flux-based models is that their solution requires reduced …