Search results for " simulation"
Article
Tools for Continuous Bioprocessing Development
Proper scale down requires good simulation of large-scale bioreactor conditions. The small-scale reactor needn’t have the same shape or geometry.
The industry needs technologies that can enable ups…
Poster
Process economy and production capacity using single-use versus stainless steel fermentation equipment
Economy simulations were based on an E. coli Dab process. Production scenarios in both single- and multi-product facilities were considered. In comparison with a stainless steel strategy, this study s…
Article
Fluid Handling in Biopharma Facilities
We made the best experiences with process simulation, which helps the user to determine the right size, mass balances, and potential bottlenecks of the production process.
With this approach, we ar…
Article
Monoclonal Antibodies Key to Unlocking the Biosimilars Market
“A very strong set of capabilities similar to those of innovator companies, including state-of-the-art analytics for determining primary and higher-order structures, animal models, simulation tools an…
Article
Determining Criticality–Process Parameters and Quality Attributes Part III: Process Control Strategies—Criticality throughout the Lifecycle
The author applies the continuum of criticality to develop the process control strategy and move through Stages 2 and 3 of the new process validation lifecycle.
With the most recent FDA …
Article
Bioprocessing Advances in Vaccine Manufacture
Advances in techniques and single-use systems are revolutionizing vaccine manufacturing.
The vaccine industry, particularly, in major Western markets, continues to be dominated by a few majo…
Article
Report from the Eighth International Plasma Product Biotechnology Meeting Melia Salinas, Lanzarote, Spain
Report from the Lanzarote meeting May 13th – 17th, 2013
Yet another well-attended and successful Plasma Product Biotechnology (PPB) meeting has been held. The meeting focu…
Article
The Development and Application of a Monoclonal Antibody Purification Platform
A purification scheme to maximize the efficiency of the purification process and product purity while minimizing the development time for early-phase therapeutic antibodies.
The following ar…