Search results for " biologic" in Articles / App Notes
Article
Recent Trends in Data Analytics for Upstream Process Workflows
Modeling techniques can improve process control and monitoring in biopharmaceutical production.
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Article
Top Process Development Trends for 2021 and a Look into 2022
… has evolved over the past 30 years, and readers how curious how to navigate the complexities of the biologic manufacturing process. According to Peggy Lio, senior director of global cell culture ser…
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Achieving the Required Buffer Quality with Inline Conditioning
To overcome this, Janssen Biologics BV decided to investigate inline conditioning (IC) technology as a buffer preparation alternative. A study was conducted to compare buffers produced with IC and buf…
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Commercial Production of Gene Therapies Using Suspension or Adherent Cell Lines
Conclusion
While suspension-based cell culture has successfully being used in scalable production of biologics resulting in high titres and low cost of goods, its application to gene therapy manuf…
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Manage HCPs and Enhance Your Route to Market
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Host cell protein (HCP) management is critical to biologics development—and getting it wrong could delay your development cycle. Learn how the right HCP strategy can enhance…
Article
Virus-like Particles as Therapeutic Moieties of the Future
About the authors
Ramesh Kumar is a graduate student, Manidipa Banerjee is a professor in the Kusuma School of Biological Sciences, and Anurag S. Rathore*, PhD, is professor in the Department of …
Article
Improving mAb Manufacturing Productivity by Optimizing Buffer and Media Prep Process Flow
Innovative approaches, including ready-to-use materials and in-line dilution, can significantly streamline overall bioprocessing operations.
By: Pranav Vengsarkar and Nandu Deorkar
I…
Article
Next Generation Process Chromatography
We really are at the start of the development journey here and that means there is so much opportunity for future improvement—both for mAbs and other biological targets. Just like single-use bioreacto…
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Step Up to GMP Manufacturing or Outsource to a CDMO: Considerations and Tips
Whether you are developing a new monoclonal antibody (mAb), cell therapy, gene therapy, or large-molecule biologic drug, the decision to tackle GMP manufacturing in-house or work with a contract devel…
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Gene Therapies Push Viral Vector Production
In addition, it is important to maintain AAV vector biological activity when removing impurities and contaminates present in a feedstock that originates from host cells or culture media. Next to this,…