Search results for " mRNA"
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Report from the 6th International HTPD Conference
Beyond mAbs: AAV and mRNA process development were discussed at HTPD 2023
Since the clinical pipeline is becoming more and more diversified, novel types of biomolecules have also become more in…
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Modern plasmid purification process
AcuraBio selects Cytiva's latest two-step purification protocol to offer a productive plasmid DNA service to its customers globally to alleviate supply constraints for mRNA and cell & gene th…
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Working With Advanced Therapeutics: You Bring the Idea, We Bring the Map
Plasmids. mRNA. Oligos. Cell and gene therapies. Antibody variants. Vaccines. We all know these advanced therapies hold huge potential. But developing them isn’t straightforward, and fai…
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Maximum Output Starts with Optimized Upstream Processing
Innovation in storage and distribution was evident with the mRNA vaccine roll-out, Bottone adds. “Modular and mobile solutions will be important for scale-up and capacity-expansion opportunities with …
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Future Downstream Process Development Solutions for Advanced Therapies
downstream
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Peter Guterstam, PhD, Product Manager of Next Generation Resins & Technologies at Cytiva, provides insight into solutions for ad…
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Techniques for Improving Process Development for Exosome-Derived Therapeutics
One cancer treatment with enormous potential is for exosomes to deliver siRNA and knock down the expression of oncogenic mRNA. The laboratory of Dr. Raghu Kalluri, one of our founders at The Universit…
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Bracing for a Future Wave of Advanced Therapies
With the help of recent investor interest, progression of advanced therapy medicinal products (ATMPs) in the clinical space continues to move forward. Buoyed by the regulatory approval of sever…
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A scalable single-use two-step plasmid purification process
While MAb processes have become much more efficient, production of mRNA and viral vectors is still hindered by the requirement for a reliable source of high-quality plasmid DNA (pDNA), which typically…
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Fundamentals of hydrophobic interaction chromatography
…s
* monoclonal antibodies (mAbs), bispecific mAbs and antibody-drug conjugates (ADC)
* mRNA
* plasmid
New to HIC? Browse this HIC resource library, containing our recently updat…
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Approaches to scaling up Chromatography Processes
Scaling up chromatography resins requires a thorough understanding of their intended use.
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